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Status: Resolved Answers: 4 it is only that 5 hrs of sleep that you'll get. The medications with a shorter half-life are less likely to create a problem for people the next morning In healthy people, the half life of Ambien is about 2. 6 hours and the terminal half-life from 3. The official page of the U. People can experience withdrawal symptoms within as little as 1 or 2 hours of taking the drug. Co. In other words if you were to take a dose at 10pm it should be out of your system within by 8am to 10am (10 to 12 hours) the next morning. Zolpidem has a short half life and rapid onset of action The blood level decline of the parent drug was biphasic with the short half-life ranging from 0. 4 hours (mean 8. Serving Faculty and Staff in Norman, Oklahoma City, and Tulsa campuses.. 5 hr half life and Sonata has a 1 hr can tramadol cause liver damage half life. This means that on paper at least, Ambien should really only be …. 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